USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: TPM2_HUMAN USC-OGP 2-DE database:  TPM2_HUMAN TPM2_HUMAN General information about the entry View entry in simple text format Entry name TPM2_HUMAN Primary accession number P06468 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Tropomyosin beta chain; AltName: Full=Beta-tropomyosin; AltName: Full=Tropomyosin-2;. Gene name Name=TPM2 Synonyms=TMSB Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0107: pI=4.67; Mw=38609 Cross-references UniProtKB/Swiss-Prot P07951; TPM2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TPM2_HUMAN Primary accession number P07951 Secondary accession number(s) A6NM85 P06468 Q13894 Q53FM4 Q5TCU4 Q5TCU7 Q9UH67 Sequence was last modified on  August 1, 1988 (version 1) Annotations were last modified on  March 15, 2017 (version 179) Name and origin of the protein Description RecName: Full=Tropomyosin beta chain; AltName: Full=Beta-tropomyosin; AltName: Full=Tropomyosin-2; Gene name Name=TPM2 Synonyms=TMSB Encoded on Name=TPM2; Synonyms=TMSB Keywords Acetylation; Actin-binding; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Isopeptide bond; Muscle protein; Nemaline myopathy; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M12126; AAA61229.1; -; mRNA EMBL M12125; AAA36773.1; -; mRNA EMBL X06825; CAA29971.1; -; mRNA EMBL M75165; AAB59509.1; -; mRNA EMBL M74817; AAA61230.1; -; mRNA EMBL AK223258; BAD96978.1; -; mRNA EMBL AL133410; CAI10974.1; -; Genomic_DNA EMBL AL133410; CAI10977.1; -; Genomic_DNA EMBL CH471071; EAW58354.1; -; Genomic_DNA EMBL BC011776; AAH11776.1; -; mRNA EMBL AF209746; AAF17621.1; -; Genomic_DNA EMBL J05247; AAA51842.1; -; Genomic_DNA CCDS CCDS6586.1; -. [P07951-2]; . CCDS CCDS6587.1; -. [P07951-1]; . PIR A23562; A23562; . PIR S00922; S00922; . RefSeq NP_003280.2; NM_003289.3. [P07951-1]; . RefSeq NP_998839.1; NM_213674.1. [P07951-2]; . RefSeq XP_016870580.1; XM_017015091.1. [P07951-1]; . UniGene Hs.300772; -; . ProteinModelPortal P07951; -; . SMR P07951; -; . BioGrid 113022; 122; . IntAct P07951; 43; . MINT MINT-94363; -; . STRING 9606.ENSP00000354219; -; . iPTMnet P07951; -; . PhosphoSitePlus P07951; -; . BioMuta TPM2; -; . DMDM 136090; -; . DOSAC-COBS-2DPAGE P07951; -; . REPRODUCTION-2DPAGE IPI00220709; -; . UCD-2DPAGE P07951; -; . EPD P07951; -; . MaxQB P07951; -; . PaxDb P07951; -; . PeptideAtlas P07951; -; . PRIDE P07951; -; . DNASU 7169; -; . Ensembl ENST00000360958; ENSP00000354219; ENSG00000198467. [P07951-1]; . Ensembl ENST00000378292; ENSP00000367542; ENSG00000198467. [P07951-2]; . GeneID 7169; -; . KEGG hsa:7169; -; . UCSC uc003zxs.4; human. [P07951-1]; . CTD 7169; -; . DisGeNET 7169; -; . GeneCards TPM2; -; . GeneReviews TPM2; -; . HGNC HGNC:12011; TPM2; . HPA HPA009066; -; . HPA HPA047089; -; . HPA HPA053624; -; . MalaCards TPM2; -; . MIM 108120; phenotype; . MIM 190990; gene; . MIM 601680; phenotype; . MIM 609285; phenotype; . neXtProt NX_P07951; -; . OpenTargets ENSG00000198467; -; . Orphanet 171881; Cap myopathy; . Orphanet 171439; Childhood-onset nemaline myopathy; . Orphanet 2020; Congenital fiber-type disproportion myopathy; . Orphanet 1146; Digitotalar dysmorphism; . Orphanet 1147; Sheldon-Hall syndrome; . Orphanet 171436; Typical nemaline myopathy; . PharmGKB PA36691; -; . eggNOG KOG1003; Eukaryota; . eggNOG ENOG410XR5K; LUCA; . GeneTree ENSGT00550000074494; -; . HOVERGEN HBG107404; -; . InParanoid P07951; -; . KO K10374; -; . OMA TEPTHEC; -; . PhylomeDB P07951; -; . TreeFam TF351519; -; . Reactome R-HSA-390522; Striated Muscle Contraction; . Reactome R-HSA-445355; Smooth Muscle Contraction; . ChiTaRS TPM2; human; . GeneWiki TPM2; -; . GenomeRNAi 7169; -; . PRO PR:P07951; -; . Proteomes UP000005640; Chromosome 9; . Bgee ENSG00000198467; -; . CleanEx HS_TPM2; -; . ExpressionAtlas P07951; baseline and differential; . Genevisible P07951; HS; . GO GO:0005884; C:actin filament; IBA:GO_Central; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005862; C:muscle thin filament tropomyosin; TAS:ProtInc; . GO GO:0003779; F:actin binding; IDA:UniProtKB; . GO GO:0051015; F:actin filament binding; IBA:GO_Central; . GO GO:0008307; F:structural constituent of muscle; TAS:ProtInc; . GO GO:0007015; P:actin filament organization; IBA:GO_Central; . GO GO:0006936; P:muscle contraction; IBA:GO_Central; . GO GO:0030049; P:muscle filament sliding; TAS:Reactome; . GO GO:0043462; P:regulation of ATPase activity; IDA:UniProtKB; . InterPro IPR000533; Tropomyosin; . Pfam PF00261; Tropomyosin; 1; . PRINTS PR00194; TROPOMYOSIN; . PROSITE PS00326; TROPOMYOSIN; 1; .

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